Yes! We believe this product is nightshade free as there are no nightshade ingredients listed on the label.

Is Doctor's Best Fully Active B12 -- 1500 mcg - 60 Veggie Caps Nightshade Free?

Yes! We believe this product is nightshade free as there are no nightshade ingredients listed on the label.
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Ingredients

Cellulose, Modified Cellulose (Vegetarian Capsule)

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Nightshade Free? Doctor's Best Fully Active B12 -- 1500 mcg - 60 Veggie Caps | Spoonful